Common Prescription Drugs Shown to Work Only 14% of Time

Common Prescription Drugs Shown to Work Only 14% of Time

Americans now spend over $250 billion a year on prescription drugs- more than do all the people in Australia, Canada, France, Germany, Italy, Japan, Spain, Brazil, Argentina, Mexico, New Zealand, and the United Kingdom combined!

Studies show that drugs as a whole, work for as few as 25% of those who take them. And our growing reliance on these ever more expensive “me too drugs” is creating huge profits for drug companies while ordinary Americans are struggling to pay their health insurance premiums. Between 1998 and 2002, the FDA approved 415 new drugs.

Only 14% of these newly approved drugs were actually uniquely different or innovative in their design.

The other 86% were old drug formulas masquerading as new innovative therapies. 

For example, there are six cholesterol-lowering statins on the market right now, five SSRI anti-depressant drugs, and at least nine ACE inhibitors to treat high blood pressure.

The Medicare prescription drug benefit only made matters worse for health care consumers.

The plan prohibited Medicare from negotiating drug prices, even though those prices continue to rise much faster than inflation.

Representative Billy Tauzin, the Louisiana Republican and former chair of the House Energy and Commerce Committee (which oversees the drug industry) co- sponsored the drug bill, was rewarded with a high-paying job as chief executive of the pharmaceutical industry's trade association. Go figure.

Notice the cost and profit margin for the following drugs and see some of the over the counter bargains that often work as well.

Celebrex:  100 mg

Consumer price (100 tablets): $130

Cost of general active ingredients: $ 0 .60

Percent markup: 21,712%

Over the counter non-steroidal anti-inflammatory drugs or NSAIDS like Advil cost $15 for 200, 200mg capsules- a prescription strength dose would be 800mg up to 3 times a day. A bargain.

Claritin: 10mg

Consumer Price (100 tablets): $215  

Cost of general active ingredients: $0 .71

Percent markup: 30,306%

The over the counter antihistamine Zyrtec sells for $14 a month.

Sinupret® by Bionorica, has been the #1 most widely recommended, scientifically tested nasal and sinus support formula in Germany for children for more than 70 years and retails for less than $25.

I recommend Sinupret to my patients with seasonal allergies and it works like a charm.

Lipitor: 20mg

Consumer Price (100 tablets): $272

Cost of general active ingredients: $5.80

Percent markup: 4,696%

Zocor: 40mg

Consumer price (100 tablets): $350. 27

Cost of general active ingredients: $8.  63

Percent markup: 4,059%

The natural over the counter lipid lowering herbal, gugulipid, 

reduces total cholesterol by 24%, triglycerides by 23%, and raises HDL by 16 percent.

A month supply of gugulipid costs around $25.

I recommend gugulipid for my patients extremely elevated cholesterol levels.

Paxil: 20mg

Consumer price (100 tablets): $220

Cost of general active ingredients: $7.60

Percent markup: 2,898%

Prozac: 20mg

Consumer price (100 tablets): $247

Cost of general active ingredients: $0 .11

Percent markup: 224,973%

Zoloft: 50mg

Consumer price: $206

Cost of general active ingredients: $1.75

Percent markup: 11,821%

There are over 100 peer-reviewed studies showing that S-adenosyl-methionine (SAMe) is a safe and effective antidepressant. It increases the action of several neurotransmitters including serotonin, norepinephrine, and dopamine.

A review of 23 randomized double-blind, placebo-controlled studies involving 1,757 people with mild to moderate depression shows that the herb St. John’s Wort is as effective as prescription antidepressants.

And studies comparing the over the counter, amino acid 5HTP, to SSRI’s  and older antidepressants have consistently shown that 5HTP is as good, if not better, than the prescription antidepressant drugs.

Prevacid: 30mg

Consumer price (100 tablets): $44

Cost of general active ingredients: $1 .01

Percent markup: 34,136%

Prilosec: 20mg

Consumer price (100 tablets): $360

Cost of general active ingredients $0 .52

Percent markup: 69,417%

Over the counter Zantac costs $14 a month.

Even better, consider using natural over the counter digestive enzymes $15-$26 a month.

But drugs have to be expensive, right? All that money is needed for

research and development. Right?

Don’t believe it! Only about 14% of Fortune 500 drug-company

revenues are applied toward research and development, while over 30% is devoted toward marketing.

Truth health doesn't come from a drug. No one has a drug deficiency.

If your a health care bargain shopper drug therapy is best avoided when possible.

The Medical Myths of Cholesterol-What You Need to Know About Heart Disease

The Medical Myths of Cholesterol-What You Need to Know About Heart Disease

 Cardiovascular disease kills almost one million Americans each year. This number accounts for 41 percent of all deaths in the United States. In fact, cardiovascular disease claims more lives than the next eight leading causes of death combined, including cancer, accidents, and AIDS. And, despite an aggressive campaign launched by the American Heart Association to counter the epidemic of heart disease, one person dies every 33 seconds. For nearly four decades, we have relied on medical myths to guide us in our attempts to prevent and treat cardiovascular disease. We have been told to reduce our cholesterol, saturated- fat intake, and to take lipid-lowering medications. Unfortunately, these recommendations have been shown to actually increase the risk of premature death, strokes, heart attacks, depression, suicide, senile dementia, and congestive heart failure.

Medical Myth Number One

Most health organizations and the public at-large are sold on the idea that high cholesterol is the main cause of arteriosclerosis and heart disease.

However, a growing body of research is dispelling this medical myth. The prestigious medical journal, The Lancet, reported in 1994 that most individuals with coronary artery disease have normal cholesterol levels!  Forty percent of all heart attacks occur in individuals with normal cholesterol levels. The Journal of the American Medical Association reports that there is no evidence linking high cholesterol levels in women with heart disease. In fact, low cholesterol levels, especially after the age of forty-seven, increase the risk of heart attack, stroke, depression, and early death. As reported in The Journal of Cardiology, “low cholesterol increases the risk of a heart attack.”

To cite the medical experts from the famous Framingham study: For each 1 mg/dl drop of cholesterol there was an 11 percent increase in coronary and total mortality (death from all sources).

Your body needs cholesterol. Cholesterol makes up eight percent of brain-matter. It is essential for proper brain function. The importance of cholesterol is far reaching. Cholesterol is the precursor to vitamin D and other hormones that are needed for sustaining a healthy life. Cholesterol is one of the key substances at nerve synapses needed to transmit information. Cholesterol helps regulate brain chemicals known as neurotransmitters. Low cholesterol can cause depression, fatigue and neurological disorders (nerve pain, tingling and numbness).

Individuals with low cholesterol are three times more likely to suffer from depression as normal adults.

Medical Myth Number Two

Cholesterol lowering drugs are a safe and effective way to prevent heart attacks and strokes.

Over the last twenty years, the pharmaceutical companies have promoted cholesterol-lowering statin drugs with such fervor that they’ve become household names: Lipitor, Crestor, Vytorin, Zocor, and others. Sixteen million Americans take Lipitor, the most popular statin drug. Statin sales in the U.S. alone are over 12.5 billion dollars a year.

No doubt, the statins lower cholesterol levels and perhaps do lower the risk of dying from a heart attack, at least in patients who already have had one, but the size of the effect is unimpressive. In one of the experiments for instance, the CARE trial, the odds of escaping death from a heart attack for a patient with manifest heart disease was 94.3 %, which improved to 95.4 % with statin treatment. This is a difference of 1.1 percent. Surely not worth all the hype these medications have received. Especially since the potential side effects from these drugs may include congestive heart failure.

The acknowledged side effects of statins include muscle pain and weakness, nerve damage, and a potentially fatal muscle-wasting disorder called rhabdomyolysis. One statin, Baycol, has been withdrawn because it was linked to 31 deaths from rhabdomyolysis. Interference with production of Co-Q10 by statin drugs is the most likely explanation. The heart is a muscle and it cannot work when deprived of the essential nutrient, Co-Q10. A deficiency of CoQ10 can lead to nerve damage and congestive heart failure.

While heart attacks have slightly declined, CHF (congestive heart failure) has more than doubled since Lipitor and other statins were first prescribed in 1987.

Taking statins for one year raised the risk of nerve damage by about 15 percent. Researchers studying CoQ10 have estimated that as little as a 25 percent reduction in bodily CoQ10 will trigger various disease processes, including high blood pressure, coronary artery disease, cancer, immune dysfunction, and fatigue.

Medical Myth Number Three

The drugs used to treat chest pain, high blood pressure, and congestive heart failure are safe and effective.

Nothing could be further from the truth. These drugs are dangerous. Calcium Channel blocking drugs (Cardizem, Procardia, Calan, Norvasc, and others) increase the risk of having a heart attack by five-fold.

Beta-blocking drugs (Atenolol, Inderal, Toprol, Tenormin, and others) may cause congestive heart failure, heart block, depression, type II diabetes, tingling in the hands and feet, fatigue, and many other unwanted side effects.

Diuretics increase the risk of developing type II diabetes by fifty percent.

Medical Myth Number Four

Heart surgery, including coronary bypass and angioplasty are safe, effective, and proven procedures.

In fact, neither surgery has been subjected to double blind placebo controlled trials. The National Institute of Health (NIH) has estimated that 90 percent of Americans who undergo bypass surgery receive no benefits. A Swedish study revealed that 12 percent of those undergoing bypass suffered obvious brain damage, including strokes. Other studies have shown that the majority of patients are more likely to die from the surgery, up to 10 percent, than a heart attack. Studies also show that patients who elected not to have the surgery actually lived longer than those who did have surgery.

Medical Myth Number Five

The test to determine if someone needs heart surgery, known as an angiogram, is a safe and accurate diagnostic procedure.

Over one million angiograms are performed each year, costing over $10 billion. These tests use a long catheter with a tiny camera for the purpose of observing arterial blockages. A study that measured the blood flow in 44 blocked arteries, as demonstrated by angiogram, found that heart arteries with up to 96 percent blockage had the swiftest blood flow. While arteries with only a 40 percent blockage had a reduced flow. The authors concluded the angiogram is an unreliable diagnostic tool and should be considered worthless.

Medical Myth Number Six

Traditional medicine continues to promote these 5 medical myths while perpetuating the greatest myth ever; nutritional supplements are unregulated, aren’t proven, and are dangerous.

This is probably the most unscrupulous myth of all. The medical journals are overflowing with studies (over1, 000 of them) that demonstrate the effectiveness of various nutritional supplements for treating high blood pressure, alone. The Federal Drug Association fought for 20 years and spent millions of dollars to prevent the following statement from being used on bottles of fish oil supplements “Consumption of Omega-3 fatty acids may reduce the risk of coronary heart disease.”

Fortunately, truth and justice prevailed. A recent American Heart Association’s study showed that individuals who took 1,000mg of fish oil a day had a 41 percent reduction in heart disease and sudden death. CoQ10 supplements have been proven to be more effective in reversing congestive heart failure than traditional drugs. Normally class IV or terminally ill congestive heart patients live only a matter of days. The majority of those receiving CoQ10 survived 2 years or more.

A number of studies have shown that vitamins help prevent heart attacks and strokes. Vitamin E has been shown to cut subsequent heart attacks by 77 percent. In fact taking vitamin E reduced the chances of death from all causes by 42 percent. B vitamins have been shown to decrease the amount of plaque in the carotid (neck) arteries by 10 percent.

Traditional medicine and its political organizations, including the American Heart Association, have failed to stop the rising epidemic of heart disease. Given heart disease’s epidemic proportions and that most of the traditional therapies commonly used to treat it may actually cause more deaths than the illness itself, it’s time to put these dangerous myths to rest.

What can you do to reduce your risk of developing heart disease? Well, first of all, please quit being stressed out about fats and cholesterol. Stress will kill you, literally. Eat all the free-range eggs, meat and butter your heart desires. Increase your consumption of fruits and vegetables. Avoid hydrogenated oils and excess sugar.  Supplement your diet with a good multivitamin and at least 1,000mg of fish oil each day. Above all, avoid falling prey to the medical myths of heart disease.

About Dr. Murphree

Dr. Murphree is a board certified nutritional specialist and chiropractic physician who has been in private practice since 1990. He is the founder and past clinic director for a large integrated medical practice located on the campus of Brookwood Hospital in Birmingham Alabama. The clinic was staffed with medical doctors, chiropractors, acupuncturists, nutritionists, and massage therapists. He is the author of 5 books for patients and doctors, including "Heart Disease What Your Doctor Won't Tell You,’” "Treating and Beating Anxiety and Depression with Orthomolecular Medicine," and

"Treating and Beating Fibromyalgia and Chronic Fatigue Syndrome."

He can be reached toll free 1-888-884-9577 or at 205-879-2383 His website is at www.Treatingandbeating.com

1. Cardiovascular disease: Comparisons. American Heart Association. Statistics fact sheet, 1997.
2. Murphree, Rodger H. “Heart Disease What Your Doctor Won’t Tell You.” Harrison and Hampton Publishing Inc 2005.
3. The Lancet 1994, 344:1182-86.
4. Journal of the American Medical Association, 1995:274(14): 1152-58.
5. Krumholz HM, “Lack of association between cholesterol and coronary heart disease mortality and morbidity and all-cause mortality in persons older than 70 years.” Journal of the Amer Med Assoc 272, 1335-13340, 1990.
6. Jacobs D.” Report of the Conference on Low Blood Cholesterol: Mortality associations. Cir 86, 1046-1060, 1992.
7. Sacks FM, Pfeiffer MA, Moyle LA, Rouleau JL, Rutherford JD, “The effect of pravastatin on coronary cholesterol levels. N Engl J Med 1996; 335:1001-9.
8. Uffe Ravnskov, MD, PhD, The Cholesterol Myths, New Trends Publishing, Washington D.C. 2000.
9. Smith Dj, Southern Medical Journal 96(12):1265-1267, Dec.2003.
10. Gaist d, Neurology 2002 May 14; 58(9): 1321-2.
11. Furberg CD, Patsy BM, Meyer JV, “Nifedipine dose-related increase in mortality in patients with coronary heart disease. Cir 1995:1326-31.
12. People’s Pharmacy, 1997 AND 1998.
13. Monthly Prescribing Guide Nov 2004.
14. Peter. Sawick, correspondence, British Medical Journal, 1994:308:855.
15. New England Journal of Medicine, 1992:326:10-16.
16. Torkel A, Scandinavia Journal of Thoracic and Cardiovascular Surgery, Supplement 15, 1974.
17. Harold and Arlene Breecher. “Forty Something Forever.” Health Savers Press 2000;pg6.
18. Hueb W. “Two to eight year survival rates in patients who refused coronary bypass grafting. Am J Cardiol 1989; 63:155-159.
19. White CW, Wright CB, Doty DB, “Does visual interpretation of coronary angiogram predict the physiologic importance of a coronary stenosis?” New Eng J Med 1984; 310:819-824.
20. Judy W.V., Hall J.H., Dugan W, Folkers K.,”Coenzyme CoQ10 Reduction of Adrianmycin Cardiotoxicity. Biomedical and Clinical Aspects of Coenzyme Q10, Vol.4, pp.231-241, Elsevier Science Publ B.V., 1984.
21. Bellizzi MC, eta al., “Vitamin E and coronary heart disease: the European paradox. Eur J Clin Nutr 1994; 48:822-831.