Broad Review of FDA Trials Suggests Antidepressants Only Marginally Better than Placebo
August 24, 2010 — A new review of 4 meta-analyses of efficacy trials submitted to the US Food and Drug Administration (FDA) suggests that antidepressants are only "marginally efficacious" compared with placebo and "document profound publication bias that inflates their apparent efficacy."
"We found that out of the 4041 patients initially started on the SSRI [selective serotonin reuptake inhibitor] citalopram in the STAR*D study, and after 4 trials, only 108 patients had a remission and did not either have a relapse and/or dropped out by the end of 12 months of continuing care," lead study author Ed Pigott, PhD, a psychologist with NeuroAdvantage LLC in Clarksville, Maryland, told Medscape Medical News.
These means that only 2.7% of patients taking anti-depressants actually go into remission!
Sustained Benefit "Jaw Dropping"
"In other words, if you're trying to look at sustained benefit, you're only looking at 2.7%, which is a pretty jaw-dropping number," added Dr. Pigott.
Overall, "the reviewed findings argue for a reappraisal of the current recommended standard of care of depression," write the study authors.
Yep, I agree, pretty jaw dropping when you learn the potential side effects of taking a worthless drug.
Read the entire study at the link below-
The Truth About Anti-depressants
If you want to know the truth about anti-depressant meds take a look at my article “The Depressing Truth About Anti-depressants” which natural provides the protocols I use for my patients with mood disorders.
1 comment:
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